This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of endoscopic sphincterotomy for suspected sphincter of Oddi dysfunction on pain-related disability following cholecystectomy. The EPISOD randomized clinical trial. JAMA 2014; 311: 2101-2109.
Published: 4th December 2014
Authors: Cotton PB, Durkalski V, Romagnuolo J, Pauls Q, Fogel E, Tarnaskey P et al. et al.
Conclusion
Some 214 patients with pain after cholecystectomy were randomized. A composite outcome (including reduced symptoms and opiate requirement) scored nine and twelve months after treatment was similar between the groups: 37 per cent in the sham treatment group and 23 per cent in the sphincterotomy group improved. Manometry results were not associated with outcome.
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