The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of postoperative antibiotic administration on postoperative infection following cholecystectomy for acute acalculous cholecystitis. A randomized clinical trial. JAMA 2014; 312: 145-154.

Published: 4th December 2014

Authors: Regimbeau JM, Fuks D, Pautrat K, Mauvais F, Haccart V, Msika S et al. et al.

Conclusion

Some 414 patients underwent acute cholecystectomy. Continuation of antibiotics postoperatively for five days did not reduce the rate of postoperative infection: 15 per cent versus 17 per cent in controls. Sixty per cent of operative bile cultures were pathogen-free.

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