This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effectiveness of an extracellular matrix graft (OASIS Wound Matrix) in the treatment of chronic leg ulcers: a randomized clinical trial J Vasc Surg 2005; 41: 837-843.

Published: 1st January 2005

Authors: VAS004. Mostow EN, Haraway GD, Dalsing M, Hodde JP, King D. .

Conclusion

Porcine small intestinal submucosa was used in addition to compression in this study that included 120 patients. After 12 weeks, the new dressing healed 55 per cent of ulcers, compared to 34 per cent that had standard care (P=0.0196).

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