The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med 2014; 370: 1402-1411.

Published: 5th February 2015

Authors: Meyer G, Vicaut E, Danays T, Agnelli G, Becattini C, Beyer-Westendorf J et al. et al.

Conclusion

Death or haemodynamic decompensation were reduced in the tenecteplase (lysis) group: 2.6 versus 5.6 per cent, P=0.02. Bleeding (6.3 versus 1.2 per cent; P<0.001) and stroke (2.4 versus 0.2 per cent; P=0.003) were higher in the lysis group.

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