This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Patient-reported outcomes with anastrozole versus tamoxifen for postmenopausal patients with ductal carcinoma in situ treated with lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial. Lancet 2016; 387: 857-865.
Published: 4th February 2016
Authors: Ganz PA, Cecchni RS, Julian TB, Margolese RG, Costantino JP, Vallow LA et al. et al.
Conclusion
This investigation included 1193 women involved in a larger clinical outcome study. The symptoms caused by each of the drugs were different. In women over 60 years (where drug effect seems equivalent), choice of agent could reflect tolerability.
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