This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Randomized clinical control study of locoregional therapy combined with arsenic trioxide for the treatment of hepatocellular carcinoma. Cancer 2015; 121: 2917-2925.

Published: 11th February 2016

Authors: Wang H, Liu Y, Wang X, Liu D, Sun Z, Chun W et al. et al.

Conclusion

The addition of four courses of arsenic trioxide improved overall survival in this study that included 125 patients (P<0.05). It improved the objective response rate (82 per cent versus 59.4 per cent, χ2 = 7.650, P <0.05) and the clinical benefit rate (95.1 per cent versus 81.25 per cent, χ2 = 5.659, P < .05).

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