This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Randomized controlled trial of ultrasound-assisted, catheter-directed thrombolysis for acute intermediate risk pulmonary embolism. Circulation 2014; 129: 479-486.

Published: 14th April 2014

Authors: Kucher N, Boekstegers P, Muller OJ, Kupatt C, Beyer-Westendorf J, Heitzer T et al. et al.

Conclusion

A total of 59 patients were randomly allocated thrombolysis for 15h. The active treatment reduced right ventricular strain (relative ventricular volume) over 24h, without any major bleeding complications. Up to 90 days there was one death (in the heparin group).

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