This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Revascularization versus medical therapy for renal artery stenosis. N Engl J Med 2009; 361: 1953-1562.
Published: 1st January 2009
Authors: The ASTRAL investigators, Wheatley K, Ives N, Gray R, Kalra PA, Moss JG et al.
Conclusion
The study included 806 patients with atherosclerotic renal artery stenosis followed for five years. The two groups had similar outcomes in terms of renal or cardiovascular events, or death. Nor was there any advantage from intervention over blood pressure control. After revascularisation, patients had slightly better renal function: mean serum creatinine 1.6 micromol per litre lower, P=0.06.
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