This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

The effects of urinary trypsin inhibitor on liver function and inflammatory factors in patients undergoing hepatectomy: a prospective, randomized, controlled clinical study. Am J Surg 2011; 202: 151–157.

Published: 21st February 2012

Authors: Yang H, Mao Y, Lu X, Sang X, Du S, Zhao H et al. et al.

Conclusion

In this study that included 176 procedures, the actively treated group were given ulinastatin twice daily for three days perioperatively. The treatment protected liver function (lower bilirubin, liver enzymes, tumour necrosis factor) and reduced the duration of hospital stay, particularly after major hepatectomy.

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