The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Thromboelastogram-guided enoxaparin dosing does not confer protection from deep venous thrombosis: a randomized controlled pilot trial. J Trauma Acute Care Surg  2014; 76:

Published: 23rd July 2014

Authors: Louis SG, Van PY, Riha GM, Barton JS, Kunio NR, Underwood SJ et al. et al.

Conclusion

Eight-seven patients were enrolled and randomized to standard (30mg b.d.), or dose-adjusted enoxaparin. The latter group had a higher dose of enoxaparin (median 50mg b.d.), but this did not affect the rate of subsequent DVT: 14 per cent versus 16 per cent in the standard enoxaparin dose group.

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