This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Tinzaparin vs warfarin for treatment of acute venous thromboembolism in patients with active cancer. A randomized clinical trial. JAMA 2015; 314: 677-686.
Published: 29th October 2015
Authors: Lee AYY, Kamphuisen PW, Meyer G, Bauersachs R, Janas MS, Jarner MF et al for the CATCH Investigators et al.
Conclusion
Nine hundred patients expected to live at least six months were included. Recurrent venous thromboembolism occurred in 7.2 per cent on tinzaparin and 10.5 per cent of those on warfarin (P=0.07). There were fewer non-major bleeding complications on tinzaparin: hazard ratio 0.58, P=0.004.
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