This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Trastuzumab emtansine for residual invasive HER2-positive breast cancer. N Engl J Med 2019; 380: 617-628.
Published: 29th April 2019
Authors: Von Minckwitz G, Huang C-S, Mano MS, Loibl S, Mamounas EP, Untch M et al.
Conclusion
Some 1486 women with residual invasive disease at operation after neoadjuvant chemotherapy were included. The use of the new conjugate drug improved three year disease-free survival to 88.3 per cent compared with 77 per cent with trastuzumab alone (P<0.001).
Pubmed LinkYou may also be interested in
Scientific Surgery
Authors: Gnant M, Fitzal F, Rinnerthaler G, Steger GS, Greil-Ressler S, Balic M et al.
Scientific Surgery
Authors: Tutt ANJ, Garber JE, Kaufman B, Viale G, Fumagalli D, Rastogi P et al.
Scientific Surgery
Authors: Wang X, Wang S-S, Huang H, Cai L, Peng R-J, Lin Y et al.
Scientific Surgery
Authors: Mittendorf EA, Zhang H, Barrios CH, Saji S, Jung KH, Hegg R et al.
Scientific Surgery
Authors: Papakonstantinou A, Matikas A, Bengtsson NO, Malmstrom P, Hedayati E, Steger G et al.
Scientific Surgery
Authors: Gralow JR, Barlow WE, Paterson AHG, M’iao JL, Lew DL, Stopeck AT et al.
Scientific Surgery
Authors: Brunt AM, Haviland JS, Wheatley DA, Sydenham MA, Alhasso A, Bloomfield DJ et al.
Scientific Surgery
Authors: Su Y, Huang J, Wang S, Unger JM, Arias-Fuenzalida J, Shi Y et al.
Scientific Surgery
Authors: Yu K-D, Wu S-Y, Liu G-Y, Wu J, Di G-H, Hu Z et al.
Scientific Surgery
Authors: Nitz M, Gluz O, Clemens M, Malter W, Reimer T, Nuding B et al.
Scientific Surgery
Authors: Schmid P, Cortes J, Pusztai L, McArthur H, Kummel S, Bergh J et al.
Scientific Surgery
Authors: Whelan TJ, Julian JA, Berrang TS, Kim D-H, Germain I, Nichol AM et al.