This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials. Lancet Oncol 2020; 21: 1620-1629.
Published: 19th March 2021
Authors: Andre T, Meyerhardt J, Iveson T, Sobrero A, Yoshino T, Souglakos I et al.
Conclusion
This pooled analysis included 12,835 patients followed for a median of 72 months. In terms of overall survival after five years, three months of chemotherapy was around 0.4 per cent worse than six months, but it was suggested this finding should be put in a clinical context.
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