This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn’s Disease: a randomised, double-blind, placebo-controlled trial (ADAFI). Gut 2014; 63: 292-299.
Published: 26th August 2014
Authors: Dewint P, Hansen BE, Oldenburg B, Hommes DW, Pierik M, Ponsioen CIJ et al. et al.
Conclusion
Some 76 patients were randomly allocated additional ciprofloxacin for twelve weeks and followed for 24 weeks. Clinical response rates were higher in the ciprofloxacin group (71 versus 47 per cent, P=0.047). There was no difference between the groups at 24 weeks.
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