This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Antibiotic prophylaxis at urinary catheter removal prevents urinary tract infections: a prospective randomized trial Ann Surg 2009; 249: 573-575
Published: 1st January 2009
Authors: Pfefferkorn U, Sanlav L, Moldenhauer J, Peterli R, von Flue M, Ackermann C et al.
Conclusion
Some 205 patients were randomly allocated three doses of trimethoprim at the time of catheter removal. Treatment significantly reduced the rate of subsequent urinary infection 3 days later from 21.6 to 4.9 per cent, P<0.001. Relative risk reduction was 77.5 per cent and the number needed to treat was six.
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