This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Early corticosteroid cessation vs long-term corticosteroid therapy in kidney transplant recipients. Long-term outcomes of a randomized clinical trial. JAMA Surg 2021; 156: 307-314.
Published: 24th November 2021
Authors: Woodle ES, Gill JS, Clark S, Stewart D, Alloway R, First R et al.
Conclusion
This study included 385 patients followed for a median 15.8 years after kidney transplantation. The addition of steroids to tacrolimus and mycophenylate mofetil did not reduce allograft failure: adjusted hazard ratio 0.83, 95 per cent confidence interval 0.62 to 1.10, P=0.19.
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