This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Clinical outcome of a randomized controlled blinded trial of open versus laparoscopic Nissen fundoplication in infants and children. Ann Surg 2011; 254: 209-216.

Published: 8th December 2011

Authors: McHoney M, Wade A, Eaton S, Howard R, Kiely E, Drake D et al. et al.

Conclusion

The authors were unable to show any major clinical differences between the methods in this study that included 39 procedures. Postoperative pain, complications and duration of hospital stay were similar for both techniques.

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IMPPACT (Intravenous Monotherapy for Postoperative Perforated Appendicitis in Children Trial). Randomized clinical trial of monotherapy versus multi-drug antibiotic therapy. Ann Surg 2021; 274: 406-410.

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A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

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