This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Does fibrin glue reduce lymph leakage (pleural effusion) after extended esophagectomy? Prospective randomized clinical trial World J Surg 2003; 27: 776-781.

Published: 1st January 2003

Authors: Tachibana M, Kinugasa S, Yoshimura H, Dhar DK, Ueda S, Fujii T et al et al.

Conclusion

3ml fibrin glue was applied to the mediastinum in half of the 43 procedures studied. There were no clinical differences in outcome, but glue increased the amount of fluid in the chest drains by a volume that was significant in the first 24h (457 ml vs. 298ml, p<0.05).

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