This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Early vs. interval appendectomy for children with perforated appendicitis. Arch Surg. 2011; 146: 660–605.

Published: 18th October 2011

Authors: Blakely ML, Williams R, Dassinger MS, Eubanks JW, Fischer P, Huang EY et al. et al.

Conclusion

The overall adverse event rate was 30 per cent after early surgery and 55 per cent after interval appendicectomy (P=0.003) in this study that included 131 children under 18.Twenty-three children allocated to interval treatment required earlier surgery, and total time away from normal activities was higher in this group: 19.4 versus 13.8 days, P<0.001.

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