This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011; 377: 31–41.
Published: 7th July 2011
Authors: Rothwell PM, Fowkes FGR, Belch JFF, Ogawa H, Warlow CP, Meade TW. et al.
Conclusion
This was a study of individual patient data from trials that included people taking aspirin for at least four years; data from over 25,000 subjects were examined. Aspirin reduced the overall death rate from cancer: odds ratio 0.79, 95 per cent confidence interval 0.68 to 0.92, P=0.003. The benefit increased with duration of treatment and included many common cancers.
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