This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes. The ACOSOG Z6051 Randomized Clinical Trial. JAMA 2015; 314: 1346-1355.
Published: 15th December 2015
Authors: Fleshman J, Branda M, Sargent DJ, Boller AM, George V, Abbas M et al. et al.
Conclusion
The study included 486 procedures. Conversion rate was 11.3 per cent. The laparoscopic procedure took longer (P<0.001). Complication rates and duration of hospital stay were similar. However, the trial failed to meet non inferiority criteria for pathological outcomes.
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