This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer. The ALaCaRT Randomized Clinical Trial. JAMA 2015; 314: 1356-1363.
Published: 15th December 2015
Authors: Stevenson ARL, Solomon MJ, Lumley JW, Hewett P, Clouston AD, Gebski VJ et al et al.
Conclusion
The study included 475 procedures. The quality of surgery was high, with rates of successful resection, clear circumferential and distal margins and total mesorectal excision similar in both groups. But non inferiority was not established in this trial.
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