This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of perioperative cardiac output guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery. A randomized clinical trial and systematic review. JAMA 2014; 311: 2181-2190.
Published: 4th December 2014
Authors: Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G et al. et al.
Conclusion
Some 734 patients were included: the primary outcome was a composite including death or major defined complications. Primary outcome occurred in 37 per cent of optimized patients and 43 per cent of controls (absolute risk reduction 6.8 per cent, P=0.07).
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