This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effectiveness of triclosan-coated PDS plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial. Lancet 2014; 384: 142-152.
Published: 16th October 2014
Authors: Diener MK, Knebel P, Keiser M, Schuler P, Schiergens TS, Atanassov V et al. et al.
Conclusion
Some 1185 patients were randomly allocated abdominal wall mass closure with one of two different PDS sutures. Coating the suture with triclosan did not affect the rate of subsequent surgical site infection (14.8 versus 16.1 per cent with plain PDS, P=0.64) or serious adverse events.
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