This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effects of evidence-based strategies to reduce the socioeconomic gradient of uptake in the English NHS Bowel Cancer Screening Programme (ASCEND): four cluster-randomised controlled trials. Lancet 2016; 387: 751-759.

Published: 29th February 2016

Authors: Wardle J, von Wagner C, Kralj-Hans I, Halloran SP, Smith SG, McGregor LM et al. et al.

Conclusion

Four different additional leaflets were sent with the standard invitation in studies totalling over 700,000 participants. GP endorsement increased overall uptake (P<0.0001), and an enhanced reminder increased uptake in deprived areas (P=0.003.).

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