This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Efficacy of a single preoperative dexamethasone dose to prevent nausea and vomiting after thyroidectomy (the tPONV Study): a randomized, double-blind, placebo-controlled clinical trial. Ann Surg 2015; 262: 934-940.

Published: 8th March 2016

Authors: Tarantino I, Warschkow R, Beutner U, Kolb W, Lüthi A, Lüthi C et al. et al.

Conclusion

Dexamethasone reduced postoperative nausea and vomiting: odds ratio 0.31, 95 per cent confidence interval 0.16 to 0.61, absolute risk reduction 28 per cent; P=0.001. Number needed to treat was four. There were no major adverse events in this study that included 152 patients.

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Open preperitoneal inguinal hernia repair, TREPP versus TIPP in a randomized clinical trial. Ann Surg 2021; 274: 698-704.

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Central venous access devices for the delivery of systemic anticancer therapy (CAVA): a randomised controlled trial. Lancet 2021; 398: 403-415.

Authors: Moss JG, Wo O, Bodenham AR, Agarwal R, Menne TF, Jones BL et al.

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Randomized controlled study investigating the effect of a dedicated in-house art gallery on the recovery of patients after major oncologic surgery. Ann Surg 2021; 274: 264-270.

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Robotic versus laparoscopic ventral hernia repair. One-year results from a prospective, multicenter, blinded randomized controlled trial. Ann Surg 2021; 273: 1076-1080.

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