This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Five-year outcome after laparoscopic anterior partial versus Nissen fundoplication: four randomized trials. Ann Surg 2012; 255: 637–642.

Published: 27th August 2012

Authors: Broeders JA, Roks DJ, Jamieson GG, Devitt PG, Baigrie RJ, Watson DI et al.

Conclusion

The authors report their conclusions after four trials conducted over nearly 20 years in 461 patients. Reflux control was similar for Nissen and 180 degree fundoplication. Patients who had 90 or 180 degree fundoplication had fewer side effects than those who had the Nissen procedure. 180 degree fundoplication emerged as the optimum treatment.

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