This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Gentamicin-collagen implants to reduce surgical site infection: systematic review and meta-analysis of the randomized trials. Ann Surg 2013; 258: 59-65.

Published: 3rd October 2013

Authors: Chang WK, Srinivasa S, MacCormick AD, Hill AG

Conclusion

The study included 15 randomized trials of 6979 patients. The use of an antibiotic-impregnated implant reduced the rate of surgical site infection: odds ratio 0.51, 95 per cent confidence interval 0.33 to 0.77, P=0.001; number needed to treat = 21. The results were similar in clean, and clean-contaminated surgery.

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Open preperitoneal inguinal hernia repair, TREPP versus TIPP in a randomized clinical trial. Ann Surg 2021; 274: 698-704.

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