This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Long-term mortality after screening for colorectal cancer. N Engl J Med 2013; 369: 1106-1141.
Published: 14th April 2014
Authors: Shaukat A, Mongin SJ, Geisser MS, Lederle FA, Bond JH, Mandel JS et al. et al.
Conclusion
This was a 30 year follow-up of over 46,000 participants in a faecal occult blood screening trial. Annual testing reduced colorectal-cancer related morality (relative risk 0.68, 95 per cent confidence interval 0.56 to 0.82), as did biennial testing (0.78, 0.65 to 0.93), but neither had any significant effect on overall mortality.
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