This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX). BMJ 2013; 346: f1908.
Published: 20th June 2013
Authors: Grant AM, Cotton SC, Boachie C, Ramsay CR, Krukowski ZH, Heading RC et al. et al.
Conclusion
Of 810 patients recruited originally, 357 were randomized. After five years, the rate of fundoplication in the surgery group was 63 per cent compared to 13 per cent in the medical group. Differences in the REFLUX symptom score significantly favoured those who had surgery (P<0.001).
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