This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Optimal duration of prophylactic antibiotic administration for elective colorectal cancer surgery: a randomized, clinical trial. Surgery 2011; 149: 171–178.
Published: 5th August 2011
Authors: Suzuki T, Sadahiro S, Maeda Y, Tanaka A, Okada K, Kamijo A. et al.
Conclusion
Single dose flomoxef was compared to 3 days of prophylaxis in this trial that included 370 procedures. There did not appear to be an advantage to extended prophylaxis: surgical site infection rates were 7.2 per cent versus 8.4 per cent after single dose prophylaxis.
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