This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Perioperative hyperoxygenation and wound site infection following surgery for acute appendicitis. A randomized, prospective, controlled trial. Arch Surg 2011; 146: 464–470.

Published: 5th August 2011

Authors: Bickel A, Gurevits M, Varnos R, Ivry S, Eitan A.

Conclusion

This study included 210 patients randomly allocated to 2h of 80 per cent oxygen postoperatively. This reduced the rate of surgical site infection from 13.6 to 5.6 per cent (P=0.04), and also the duration of hospital stay: 2.92 to 2.51 days (P=0.01).

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IMPPACT (Intravenous Monotherapy for Postoperative Perforated Appendicitis in Children Trial). Randomized clinical trial of monotherapy versus multi-drug antibiotic therapy. Ann Surg 2021; 274: 406-410.

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A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

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Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.