This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled phase I/II studies Lancet 2009; 373: 1264-1274
Published: 1st January 2009
Authors: Ferguson MWJ, Duncan J, Bond J, Bush J, Durani P, So K et al et al.
Conclusion
Injection of transforming growth factor beta 3 into full thickness skin wounds improved visual analogue healing scores in two of the three studies. Positive effects were seen at all concentrations of the study drug.
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