This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Randomized comparison of surveillance intervals in familial colorectal cancer. J Clin Oncol 2015; 33: 4188-4193.
Published: 29th February 2016
Authors: Hennink SD, van Der Meulen-de Jong AE, Wolterbeek R, Crobach ASLP, Becx MCJM, Crobach WSFJ et al. et al.
Conclusion
Some 528 people with a strong family history were randomized to repeat colonoscopy after three or six years. After six years, the rate of advanced polyp detection was similar: 3.4 and 6.9 per cent, respectively. Surveillance every three years was only necessary for patients with three or more adenomas detected at colonoscopy.
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