This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Randomized study on oral administration of calcitriol to prevent symptomatic hypocalcemia after total thyroidectomy. Am J Surg 2005; 190: 424-429.
Published: 1st January 2005
Authors: Tartaglia F, Giuliani A, Sgueglia M, Biancari F, Juvonen T, Campana FP. et al.
Conclusion
A consecutive series of 417 patients undergoing total thyroidectomy with routine calcium supplementation (500mg tds) were randomized to one of three calcitriol regimens. 1mcg calcitriol twice daily gave the lowest rate of severe hypocalcaemia after three days (9.9 per cent), compared to 23.1 per cent for 0.5 mcg and 27.1 per cent in controls.
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