This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Restricted intravenous fluid regimen reduces the rate of postoperative complications and alters immunological activity of elderly patients operated for abdominal cancer: a randomized prospective clinical trial. World J Surg 2012; 36: 993–1002.

Published: 14th December 2012

Authors: Gao T, Li N, Zhang J-J, Xi F-C, Chen Q-Y, Zhu W-M et al. et al.

Conclusion

Some 179 patients were randomized to standard or restricted fluids. The restricted regimen was associated with fewer postoperative complications, especially infections (15 versus 27 per cent, P=0.04). This group also had better preservation of immune function as measured by reduced T-cell suppression.

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