This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Risk of death and amputation with use of paclitaxel-coated balloons in the infrapopliteal arteries for treatment of critical limb ischemia: a systematic review and meta-analysis of randomized controlled trials. J Vasc Intervent Radiol 2020; 31: 202-212

Published: 29th April 2020

Authors: Katsanos K, Spiliopoulos S, Kitrou P, Krokidis M, Paraskevopoulos I, Karnabatidis D et al.

Conclusion

This updated meta-analysis included eight RCTs of 1420 procedures, followed for one year. Cumulative risk of death/amputation was significantly worse following the use of paclitaxel-coated balloons: 13.7 versus 9.4 per cent, P = 0.008.

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