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Timing of chemical thromboprophylaxis and deep vein thrombosis in major colorectal surgery: a randomized clinical trial. Ann Surg 2016; 264: 632-639.

Published: 2nd February 2017

Authors: Zaghiyan KN, Sax HC, Miraflor E, Crossman D, Wagner W, Mirocha J et al.


Eighteen patients (4.2 per cent) already had a DVT preoperatively. The remaining 376 patients were randomized to additional preoperative thromboprophylaxis. Repeat scanning after 30 days showed no difference in the DVT rate: 1.6 per cent for preoperative, and 3.6 per cent for postoperative thromboprophylaxis only (P=0.34).

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