This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A double-blinded randomized clinical study on the therapeutic effect of Gastrografin® in prolonged postoperative ileus after elective colorectal surgery. World J Surg 2016; 40: 206-214.

Published: 4th February 2016

Authors: Biondo S, Miquel J, Espin-Basany E, Sanchez JL, Golda T, Ferrer AM et al. et al.

Conclusion

The study included 29 patients per group. There was no reduction in the mean time to resolution between the groups: 9.1 versus 10.3 days in controls.

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Meta-analysis, meta-regression, and GRADE assessment of randomized and nonrandomized studies of incisional negative pressure wound therapy versus control dressings for the prevention of postoperative wound complications. Ann Surg 2020; 272: 81-91.

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Incisional surgical site infection after abdominal fascial closure with Triclosan-coated barbed suture vs Triclosan-coated polydioxanone loop suture vs polydioxanone loop suture in emergent abdominal surgery. A randomized clinical trial. J Am Coll Surg 2020; 230: 766-774.

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Effect of cricoid pressure compared with a sham procedure in the rapid sequence induction of anesthesia. The IRIS Randomized Clinical Trial. JAMA Surg 2019; 154: 9-17

Authors: Birenbaum A, Hajage D, Roche S, Ntouba A, Eurin M, Cuvillon P et al.

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Effect of intraoperative high positive end-expiratory pressure (PEEP) with recruitment maneuvers vs low PEEP on postoperative pulmonary complications in obese patients. A randomized clinical trial. JAMA 2019; 321: 2305-2292

Authors: Writing Committee for the PROBESE Collaborative Group of the PROtective VEntilation Network (PROVEnet) for the Clinical Trial Network of the European Society of Anaesthesiology

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Negative pressure wound therapy for surgical-site infections. A randomized trial. Ann Surg 2019; 269: 1034-1040.

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Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial. Lancet 2018; 391: 2325-2334.

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