This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Hypothermic machine perfusion in liver transplantation — a randomized trial. N Engl J Med 2021; 384: 1391-1401.

Published: 1st November 2021

Authors: Van Rijn R, Schurink II, de Vries Y, van den Berg AP, Cerisuelo MC, Murad AD et al.

Conclusion

Use of machine perfusion reduced the rate of allograft dysfunction (26 versus 40 per cent) in this study that included 156 procedures. It also reduced the risk of non-anastomotic biliary stricture: 6 versus 18 per cent, P=0.03.

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Hypothermic oxygenated machine perfusion reduces early allograft injury and improves post-transplant outcomes in extended criteria donation liver transplantation from donation after brain death. Ann Surg 2021; 274: 705-712.

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Oxygenated end-hypothermic machine perfusion in expanded criteria donor kidney transplant. A randomized clinical trial. JAMA Surg 2021; 156: 517-525.

Authors: Husen P, Boffa C, Jochmans I, Krikke C, Davies L, Mazilescu L et al.

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Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial Lancet 2020; 396: 1653-1662.

Authors: Jochmans I, Brat A, Davies L, Hofker HS, van de Leemkolk FEM, Leuvenink HGD et al.

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Authors: Zonnebeld N, Tordoir JHM, van Loon MM, de Smet AA, Huisman LC, Cuypers PW et al.

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A randomized controlled trial of drug-coated balloon angioplasty in venous anastomotic stenosis of dialysis arteriovenous grafts. J Vasc Surg 2020; 71: 1994-2003.

Authors: Liao M-T, Lee C-P, Lin T-T, Jong C-B, Chen T-Y, Lin L et al.

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Drug-coated balloons for dysfunctional dialysis arteriovenous fistulas. N Engl J Med 2020; 383: 733-742.

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A randomized trial of vonapanitase (PATENCY-1) to promote radiocephalic fistula patency and use for hemodialysis. J Vasc Surg 2019; 69: 507-515

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Telemedicine based remote home monitoring after liver transplantation. Results of a randomized prospective trial. Ann Surg 2019; 270: 564-572.

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A prospective randomized study of stent graft placement after balloon angioplasty versus balloon angioplasty alone for the treatment of hemodialysis patients with prosthetic graft outflow stenosis. J Vasc Surg 2018; 68: 546–553.

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