This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Gentamicin-collagen sponges for the prevention of surgical site infections: a meta-analysis of randomized controlled trials. Surg Infection 2016; 17: 601-609.

Published: 30th November 2016

Authors: Konstantelias AA, Polyzos KA, Falagas ME

Conclusion

There were 21 randomized trials that studied 8472 patients. Surgical site infection was reduced in patients who had the sponge: risk ratio 0.61, 95 per cent confidence interval 0.49 to 0.84. When studies were graded according to quality, the effect was less pronounced in higher quality studies.

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