This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Haloperidol prophylaxis for preventing aggravation of postoperative delirium in elderly patients: a randomized, open-label prospective trial. Surg Today 2017; 47: 815–826.

Published: 6th October 2017

Authors: Fukata S, Kawabata Y, Fujishiro K, Kitagawa Y, Kuroiwa K, Akiyama H et al.

Conclusion

Haloperidol reduced the risk of delirium from 32 to 18.2 per cent (P= 0.02) in this study of 201 patients over 74 years old. The effects were more marked in patients with higher NEECHAM scores.

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