This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

High-dose perioperative atorvastatin and acute kidney injury following cardiac surgery. A randomized clinical trial. JAMA. 2016; 315: 877-888.

Published: 4th February 2016

Authors: Billings FT, Hendricks PA, Schildcrout JS, Shi Y, Petracek MR, Byrne JG et al. et al.

Conclusion

High-dose perioperative statin treatment compared with placebo did not reduce the risk of acute kidney injury overall among patients naïve to treatment with statins, or in patients already taking them regularly.

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Meta-analysis, meta-regression, and GRADE assessment of randomized and nonrandomized studies of incisional negative pressure wound therapy versus control dressings for the prevention of postoperative wound complications. Ann Surg 2020; 272: 81-91.

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