This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial. Lancet 2017; 390: 567-576.
Published: 6th October 2017
Authors: Jairam AP, Timmermans L, Eker HH, Pierik RE, van Klaveren D, Steyerberg EW et al.
Conclusion
Some 480 patients were studied and followed for two years. The rate of incisional hernia was lowest in those randomized to only mesh (13 per cent) compared to sublay mesh (18 per cent) or sutures (30 per cent). Wound infection rates were similar, but seroma was more frequent after onlay mesh.
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