This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A randomized, blinded, multicenter trial of a gentamicin vancomycin gel (DFA-02) in patients undergoing abdominal surgery. Surgery 2017; 213: 1003–1009.

Published: 25th January 2018

Authors: Bennett-Guerrero E, Berry SM, Bergese SD, Fleschner PR, Minkowitz HS, Segura-Vasi AM et al.

Conclusion

The study compared antibiotic gel with placebo applied to the abdominal wound during closure, or standard care, in 445 surgical procedures. The surgical site infection rate was similar in the antibiotic gel group (14.6 per cent) and the other two control groups (18.1 per cent).

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Meta-analysis, meta-regression, and GRADE assessment of randomized and nonrandomized studies of incisional negative pressure wound therapy versus control dressings for the prevention of postoperative wound complications. Ann Surg 2020; 272: 81-91.

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Authors: Devereaux PJ, Duceppe E, Guyatt G, Tandon V, Rodseth R, Biccard BM et al.