This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Rivaroxaban in peripheral artery disease after revascularization. N Engl J Med 2020; 382: 1994-2004.

Published: 22nd July 2020

Authors: Bonaca MP, Bauersachs RM, Anand S, Debus ES, Nehler MR, Patel MR et al.

Conclusion

This study included 6564 patients randomly allocated aspirin alone, or aspirin plus rivaroxaban 2.5mg b.d. The composite outcome of adverse cardiovascular events at three years was reduced by the addition of rivaroxaban (17.3 versus 19.9 per cent, P=0.009), without increasing the risk of major bleeding.

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