Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 700-708.

Authors: Wu L, Shang R, Sharma P, Zhou W, Liu J, Yao L et al.

Scientific Surgery

Short-term outcomes of robotic gastrectomy vs laparoscopic gastrectomy for patients with gastric cancer. A randomized clinical trial. JAMA Surg 2021; 156: 954-963.

Authors: Ojima T, Nakamura M, Hayata K, Kitadani J, Katsuda M, Takeuchi A et al.

Scientific Surgery

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 120-127.

Authors: Kono K, Misawa K, Yabusaki H, Kinoshita T, Lau PC, Kim YW et al.

Scientific Surgery

Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.

Scientific Surgery

Efficacy and safety of ursodeoxycholic acid for the prevention of gallstone formation after gastrectomy in patients with gastric cancer. The PEGASUS-D randomized clinical trial. JAMA Surg 2020; 155: 703-711.

Authors: Lee SH, Jang DK, Yoo M-W, Hwang S-H, Ryu S-Y, Kwon OK et al.

Scientific Surgery

Safety and efficacy of indocyanine green tracer-guided lymph node dissection during laparoscopic radical gastrectomy in patients with gastric cancer. A randomized clinical trial. JAMA Surg 2020; 155: 300-311.

Authors: Chen Q-Y, Xie J-W, Zhong Q, Wang J-B, Lin J-X, Lu J et al.

Scientific Surgery

Effect of laparoscopic distal gastrectomy vs open distal gastrectomy on long-term survival among patients with stage I gastric cancer. The KLASS-01 Randomized Clinical Trial. JAMA Oncol 2019; 5: 506-513.

Authors: Kim H-H, Han S-U, Kim M-C, Kim W, Le H-J, Ryu SW et al.

Scientific Surgery

Pouch versus no pouch following total gastrectomy: meta-analysis of randomized and non-randomized studies. Ann Surg 2019; 269: 1041-1053.

Authors: Syn N, Wee I, Shabbir A, Kim G, So JB-Y

Scientific Surgery

Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer. The CLASS-01 randomized clinical trial. JAMA 2019; 321: 1983-1992.

Authors: Yu J, Huang C, Sun Y, Su X, Cao H, Hu J et al.

Scientific Surgery

Effect of perioperative oral nutritional supplementation in malnourished patients who undergo gastrectomy: a prospective randomized trial. Surgery 2018; 164: 1263-1270.

Authors: Kong S-H, Lee H-J, Na J-R, Kim WG, Han D-S, Park S-H et al.

Scientific Surgery

Comparison of 3D laparoscopic gastrectomy with a 2D procedure for gastric cancer: a phase 3 randomized controlled trial. Surgery 2018; 163: 300-304.

Authors: Zheng C-H, Lu J, Zheng H-L, Li P, Xie J-W, Wang J-B et al.

Scientific Surgery

Laparoscopy-assisted versus open D2 distal gastrectomy for advanced gastric cancer: results from a randomized phase II multicenter clinical trial (COACT 1001). Ann Surg 2018; 267: 638-645.

Authors: Park YK, Yoon HM, Kim Y-W, Park JY, Ryu KW, Lee Y-J et al.

Scientific Surgery

Helicobacter pylori therapy for the prevention of metachronous gastric cancer. N Engl J Med 2018; 378: 1085-1095.

Authors: Choi IJ, Kook M-C, Kim Y-I, Cho S-J, Lee JY, Kim CG et al.

Scientific Surgery

Adjuvant chemoradiotherapy with epirubicin, cisplatin, and fluorouracil compared with adjuvant chemoradiotherapy with fluorouracil and leucovorin after curative resection of gastric cancer: results from CALGB 80101 (Alliance). J Clin Oncol 2017; 35: 3671-3677.

Authors: Fuchs CS, Niedzwiecki D, Mamon HJ, Tepper JE, Xing Y, Swanson RS et al.

Scientific Surgery

Roux-en-Y or Billroth II reconstruction after radical distal gastrectomy for gastric cancer: a multicenter randomized controlled trial. Ann Surg 2018; 267: 236-242.

Authors: So JB-Y, Rao J, Wong AS-Y, Chan Y-H, Pang NQ, Tay AYL et al.

Scientific Surgery

Effect of intravenous ferric carboxymaltose on hemoglobin response among patients with acute isovolemic anemia following gastrectomy. The FAIRY Randomized Clinical Trial. JAMA. 2017; 317: 2097-2104.

Authors: Kim Y-W, Bae J-M, Park Y-K, Yang H-K, Yu W, Yook JH et al.

Scientific Surgery

Randomized controlled trial to evaluate splenectomy in total gastrectomy for proximal gastric carcinoma. Ann Surg 2017; 265: 277-283.

Authors: Sano T, Sasako M, Mizusawa J, Yamamoto S, Katai H, Yoshikawa T et al.

Scientific Surgery

A randomized phase II study of the clinical effects of ultrasonically activated coagulating shears (Harmonic scalpel) in open gastrectomy for gastric cancer. Surg Today 2016; 46: 561–568.

Authors: Kawabata R, Takiguchi S, Kimura Y, Imamura H, Fujita J, Tamura S et al.

Scientific Surgery

Morbidity and mortality of laparoscopic versus open D2 distal gastrectomy for advanced gastric cancer: a randomized controlled trial. J Clin Oncol 2016; 34: 1350-1357.

Authors: Hu Y, Huang C, Sun Y, Su X, Cao H, Hu J et al.

Scientific Surgery

A randomized controlled trial of vagus nerve-preserving distal gastrectomy versus conventional distal gastrectomy for postoperative quality of life in early stage gastric cancer patients. Ann Surg 2016; 263: 1079-1084.

Authors: Kim S, Cho J, Kang D, Oh SJ, Kim AR, Sohn TS et al.

Scientific Surgery

Phase III trial to compare adjuvant chemotherapy with capecitabine and cisplatin versus concurrent chemoradiotherapy in gastric cancer: final report of the adjuvant chemoradiotherapy in stomach tumors trial, including survival and subset analyses. J Clin Oncol 2015; 33: 3130-3136.

Authors: Park SH, Sohn TS, Lee J, Lim DH, Hong ME, Kim K-M et al. et al.

Scientific Surgery

Decreased morbidity of laparoscopic distal gastrectomy compared with open distal gastrectomy for stage I gastric cancer: short-term outcomes from a multicenter randomized controlled trial (KLASS-01). Ann Surg 2016; 263: 28-35.

Authors: Kim W, Kim H-H, Han S-U, Kim M-C, Hyung WJ, Ryu SW et al on behalf of the Korean Laparo-endoscopic Gastrointestinal Surgery Study (KLASS) Group et al.

Scientific Surgery