Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Hybrid minimally invasive esophagectomy for esophageal cancer. N Engl J Med 2019; 380: 152-162.

Authors: Mariette C, Markar SR, Dabakuyo-Yonli TS, Meunier B, Pezet D, Collet D et al.

Scientific Surgery

Neoadjuvant chemoradiotherapy followed by surgery versus surgery alone for locally advanced squamous cell carcinoma of the esophagus (NEOCRTEC5010): a phase III multicenter, randomized, open-label clinical trial. J Clin Oncol 2018; 36: 2796-2803.

Authors: Yang H, Liu Y, Chen Y, Zhu C, Fang W, Yu Z et al.

Scientific Surgery

Effectiveness of fibrin sealant application on the development of staple line complications after sleeve gastrectomy: a prospective randomized trial. Ann Surg 2018; 268: 762-768.

Authors: Rebibo L, Dhahri A, Chati R, Cosse C, Huet E, Regimbeau J-M et al.

Scientific Surgery

The RESTORE randomized controlled trial: impact of a multidisciplinary rehabilitative program on cardiorespiratory fitness in esophagogastric cancer survivorship. Ann Surg 2008; 268: 747-755.

Authors: O’Neill L, Guinan E, Doyle S, Bennett AE, Murphy C, Elliott JA et al.

Scientific Surgery

Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 2018; 320: 1259-1265.

Authors: Salminen P, Hannu Paajanen T, Rautio T, Nordström P, Aarnio M, Rantanen T et al.

Scientific Surgery

Randomized trial of division versus nondivision of short gastric vessels during Nissen fundoplication: 20-year outcomes. Ann Surg 2018; 268: 228-232.

Authors: Kinsey-Trotman SP, Devitt PG, Bright T, Thompson SK, Jamieson GG, Watson DI et al.

Scientific Surgery

Esomeprazole and aspirin in Barrett’s oesophagus (AspECT): a randomised factorial trial. Lancet 2018; 392: 400–8.

Authors: Jankowski JAZ, de Caestecker J, Love SB, Reilly G, Watson P, Sanders S et al.

Scientific Surgery

Comparison of 3D laparoscopic gastrectomy with a 2D procedure for gastric cancer: a phase 3 randomized controlled trial. Surgery 2018; 163: 300-304.

Authors: Zheng C-H, Lu J, Zheng H-L, Li P, Xie J-W, Wang J-B et al.

Scientific Surgery

Extended right thoracic approach compared with limited left thoracic approach for patients with middle and lower esophageal squamous cell carcinoma: three-year survival of a prospective, randomized, open-label trial. Ann Surg 2018; 267: 826-832.

Authors: Li B, Hu H, Zhang Y, Zhang J, Miao L, Ma L et al.

Scientific Surgery

Laparoscopy-assisted versus open D2 distal gastrectomy for advanced gastric cancer: results from a randomized phase II multicenter clinical trial (COACT 1001). Ann Surg 2018; 267: 638-645.

Authors: Park YK, Yoon HM, Kim Y-W, Park JY, Ryu KW, Lee Y-J et al.

Scientific Surgery

Comparison of superficial surgical site infection between delayed primary versus primary wound closure in complicated appendicitis: a randomized controlled trial. Ann Surg 2018; 267: 631-637.

Authors: Siribumrungwong B, Chantip A, Noorit P, Wilasrusmee C, Ungpinitpong W, Chotiya P et al.

Scientific Surgery

Early oral feeding following McKeown minimally invasive esophagectomy: an open-label, randomized, controlled, noninferiority trial. Ann Surg 2018; 267: 435-442.

Authors: Sun H-B, Li Y, Liu X-B, Zhang R-X, Wang Z-F, Lerut T et al.

Scientific Surgery

Helicobacter pylori therapy for the prevention of metachronous gastric cancer. N Engl J Med 2018; 378: 1085-1095.

Authors: Choi IJ, Kook M-C, Kim Y-I, Cho S-J, Lee JY, Kim CG et al.

Scientific Surgery

Optimal stump management in laparoscopic appendectomy: a network meta-analysis by the Minimally Invasive Surgery Synthesis of Interventions and Outcomes Network. Surgery 2017: 162: 994-1005.

Authors: Antoniou SA, Mavridis D, Hajibandeh S, Antoniou GA, Gorter R, Tenhagen M et al.

Scientific Surgery

Adjuvant chemoradiotherapy with epirubicin, cisplatin, and fluorouracil compared with adjuvant chemoradiotherapy with fluorouracil and leucovorin after curative resection of gastric cancer: results from CALGB 80101 (Alliance). J Clin Oncol 2017; 35: 3671-3677.

Authors: Fuchs CS, Niedzwiecki D, Mamon HJ, Tepper JE, Xing Y, Swanson RS et al.

Scientific Surgery

Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs). EJSO 2017; 43: 1550-1558.

Authors: Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Nowak K, Kieser M et al.

Scientific Surgery

Roux-en-Y or Billroth II reconstruction after radical distal gastrectomy for gastric cancer: a multicenter randomized controlled trial. Ann Surg 2018; 267: 236-242.

Authors: So JB-Y, Rao J, Wong AS-Y, Chan Y-H, Pang NQ, Tay AYL et al.

Scientific Surgery

Circular stapling versus triangulating stapling for the cervical esophagogastric anastomosis after esophagectomy in patients with thoracic esophageal cancer: A prospective, randomized, controlled trial. Surgery 2017; 162: 131-138.

Authors: Hayata K, Nakamori M, Nakamura M, Ojima T, Iwahashi M, Katsuda M et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity. The SM-BOSS randomized clinical trial. JAMA 2018; 319: 255-265.

Authors: Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D , Borbély Y et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity. The SLEEVEPASS randomized clinical trial. JAMA 2018; 319: 241-254.

Authors: Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P et al.

Scientific Surgery

Effect of tight control management on Crohn’s disease (CALM): a multicentre, randomised, controlled phase 3 trial. Lancet 2017; 390: 2779-2789.

Authors: Colombel J-F, Panaccione R, Bossuyt P, Lukas M, Baert F, Vaňásek T et al.

Scientific Surgery

A randomised trial of endoscopic submucosal dissection versus endoscopic mucosal resection for early Barrett’s neoplasia. Gut 2017; 66: 783-793.

Authors: Terheggen G, Horn EM, Vieth M, Gabbert H, Enderle M, Neugebauer A et al.

Scientific Surgery

Does prolonged enteral feeding with supplemental omega-3 fatty acids impact on recovery post-esophagectomy: results of a randomized double-blind trial. Ann Surg 2017; 266: 720-728.

Authors: Healy LA, Ryan A, Doyle S, Ní Bhuachalla EB, Cushen S, Segurado R et al.

Scientific Surgery

Minimally invasive versus open esophageal resection: three-year follow-up of the previously reported randomized controlled trial: The TIME Trial. Ann Surg 2017; 266: 232-236.

Authors: Straatman J, van der Wielen N, Cuesta MA, Daams F, Roig Garcia J, Bonavina L et al.

Scientific Surgery

Seventeen-year outcome of a randomized clinical trial comparing laparoscopic and conventional Nissen fundoplication: a plea for patient counseling and clarification. Ann Surg 2017; 266: 23-28.

Authors: Oor J, Roks D, Broeders J, Hazebroek E, Gooszen H

Scientific Surgery

Antibiotics versus surgical therapy for uncomplicated appendicitis: systematic review and meta-analysis of controlled trials (PROSPERO 2015: CRD42015016882). Ann Surg 2017; 265: 889-900.

Authors: Harnoss J, Zelienka I, Probst P, Grummich K, Müller-Lantzsch C, Harnoss J et al.

Scientific Surgery

Effect of intravenous ferric carboxymaltose on hemoglobin response among patients with acute isovolemic anemia following gastrectomy. The FAIRY Randomized Clinical Trial. JAMA. 2017; 317: 2097-2104.

Authors: Kim Y-W, Bae J-M, Park Y-K, Yang H-K, Yu W, Yook JH et al.

Scientific Surgery

Laparoscopic sleeve gastrectomy versus Roux-Y-gastric bypass for morbid obesity: 3-year outcomes of the prospective randomized Swiss Multicenter Bypass Or Sleeve Study (SM-BOSS). Ann Surg 2017; 265: 466-473.

Authors: Peterli R, Wölnerhanssen BK, Vetter D, Nett P, Gass M, Borbély Y et al.

Scientific Surgery

Survival after neoadjuvant and adjuvant treatments compared to surgery alone for resectable esophageal carcinoma: a network meta-analysis. Ann Surg 2017; 265: 481-491.

Authors: Pasquali S, Yim G, Vohra R , Mocellin S, Nyanhongo D, Marriott P et al.

Scientific Surgery

Peri-operative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma (UK Medical Research Council ST03): primary analysis results of a multicentre, open-label, randomised phase 2-3 trial. Lancet Oncol 2017; 18: 357-370.

Authors: Cunningham D, Stenning SP , Smyth EC, Okines AF, Allum WH, Rowley S et al.

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