This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Adverse events and postoperative complications in a randomized trial of preoperative short-course radiotherapy versus long-course chemoradiotherapy for T3 adenocarcinoma of the rectum: Trans-Tasman Radiation Oncology Group Trial (TROG 01.04). Ann Surg 2017; 265: 882-888.

Published: 14th June 2017

Authors: Ansari N, Solomon MJ , Fisher RJ, Mackay J, Burmeister B, Ackland S et al.

Conclusion

Postoperative complication rates were similar, but there was a higher incidence of adverse events (at least one of dermatitis, nausea, diarrhoea) in patients who had long-course, compared to short-course radiotherapy: 99.4 versus 72.3 per cent, P<0.001.

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