Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Management of extremity fasciotomy sites prospective randomized evaluation of two techniques. Am J Surg 2018; 216: 736–739.

Authors: Johnson LS, Chaar M, Ball CG, Perez S, Nicholas JM, Wyrzykowski AD et al.

Scientific Surgery

Thromboembolism incidence and prophylaxis use after gastrectomy among Korean patients with gastric adenocarcinoma. The PROTECTOR randomized clinical trial. JAMA Surg 2018; 153: 939-946.

Authors: Jung YJ, Seo HS, Park CH, Jeon HM, Kim J-I, Yim HW et al.

Scientific Surgery

Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high-risk transient ischaemic attack. BMJ 2018; 363: k5108.

Authors: Hao Q, Tampi M, O’Donnell M, Foroutan F, Siemieniuk RAC, Guyatt G et al.

Scientific Surgery

Risk of death following application of paclitaxel-coated balloons and stents in the femoropopliteal artery of the leg: a systematic review and meta-analysis of randomized controlled trials. J Am Heart Assoc 2018; 24: e011245.

Authors: Katsanos K, Spiliopoulos S, Kitrou P, Krokidis M, Karnabatidis D

Scientific Surgery

Venous thromboembolism incidence and prophylaxis use after gastrectomy among Korean patients with gastric adenocarcinoma. The PROTECTOR randomized clinical trial. JAMA Surg 2018; 153: 939-946.

Authors: Jung YJ, Seo HS, Park CY, Jeon HM, Kim J-I, Yim HW et al.

Scientific Surgery

Successful percutaneous access for endovascular aneurysm repair is significantly cheaper than femoral cutdown in a prospective randomized trial. J Vasc Surg 2018; 68: 384-391.

Authors: Uhlmann ME, Walter C, Taher F, Plimon M, Falkensammer J, Assadian A et al.

Scientific Surgery

Wearable sensor technology efficacy in peripheral vascular disease (wSTEP). A randomized controlled trial. Ann Surg 2018; 268: 1113-1118.

Authors: Normahani P, Kwasnicki R, Bicknell C, Allen L, Jenkins MP, Gibbs R et al.

Scientific Surgery

Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial. Lancet Diabetes Endocrinol 2018; 6: 186–196.

Authors: Edmonds M, Lazaro-Martinez JL, Alfayate-Garcia JM, Martini J, Petit J-M, Rayman G et al.

Scientific Surgery

LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial. Lancet Diabetes Endocrinol 2018; 6: 870-878.

Authors: Game F, Jeffcoate W, Tarnow L, Jacobsen JL, Whitham DJ, Harrison EF et al.

Scientific Surgery

Systematic review and meta-analysis of clinical trials examining the benefit of exercise programmes using Nordic Walking in patients with peripheral artery disease. Eur J Vasc Endovasc Surg 2018; 56: 534–543.

Authors: Golledge J, Maarij K, Moxon JV, Beard JD, Girold S, Wrang H et al.

Scientific Surgery

Prospective, double-blind, randomized controlled trial comparing electrocoagulation and radiofrequency in the treatment of patients with great saphenous vein insufficiency and lower limb varicose veins. J Vasc Surg Venous Lymphatic 2018; 6: 212-219.

Authors: Beteli CB, Rossi FH, de Almeida BL, Izukawa NM, Rossi CBO, Gabriel SA et al.

Scientific Surgery

Individualised versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome (IDEAL DVT): a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial. Lancet Haematol 2018; 1: e25-e33.

Authors: Ten Cate-Hoek AJ, Amin EE, Bouman AC, Meijer K, Tick LW, Middeldorp S et al.

Scientific Surgery

Systematic review and meta-analysis of randomized controlled trials evaluating long-term outcomes of endovenous management of lower extremity varicose veins. J Vasc Surg Venous Lymphat Disord 2018; 6: 256-270.

Authors: Kheirelseid EAH, Crowe G, Sehgal R, Liakopoulos D, Bela H, Mulkern E et al.

Scientific Surgery

A randomised clinical trial comparing n-butyl cyanoacrylate, radiofrequency ablation and endovenous laser ablation for the treatment of superficial venous incompetence: two year follow up results. Eur J Vasc Endovasc Surg 2018; 56: 553-560.

Authors: Eroglu E, Alptekin Y

Scientific Surgery

Randomized double-blinded study comparing medical treatment versus iliac vein stenting in chronic venous disease. J Vasc Surg Venous Lymphatic 2018; 6: 183-191.

Authors: Rossi FH, Kambara AM, Izukawa NM, Rodrugues TO, Rossi CB, Sousa AG et al.

Scientific Surgery

A polymer-coated, paclitaxel eluting stent (Eluvia) versus a polymer-free, paclitaxel-coated stent (Zilver PTX) for endovascular femoropopliteal intervention (IMPERIAL): a randomized non-inferiority trial. Lancet 2018; 392: 1541-1551.

Authors: Gray WA, Keirse K, Soga Y, Benko A, Babaev A, Yokoi Y et al.

Scientific Surgery

No clinical benefit of intramuscular delivery of bone marrow-derived mononuclear cells in nonreconstructable peripheral arterial disease: results of a phase-III randomized-controlled trial. Ann Surg 2018; 268: 756-761.

Authors: Lindeman J, Zwaginga J, Kallenberg-Lantrua G, van Wissen RC, Schepers A, van Bockel HJ et al.

Scientific Surgery

Closed incision negative pressure therapy reduces surgical site infections in vascular surgery: a prospective randomised trial (AIMS Trial). Eur J Vasc Endovasc Surg 2018; 56: 442-448.

Authors: Gombert A, Babilon M, Barbati ME, Keszei A, von Trotha KT, Jalaie H et al.

Scientific Surgery

A systematic review of the efficacy of aspirin monotherapy versus other antiplatelet therapy regimens in peripheral arterial disease. J Vasc Surg 2018; 67: 1922-1932.

Authors: Beiswenger AC, Jo A, Harth K, Kumins NH, Shishehbor MH, Kashyap VS et al.

Scientific Surgery

HYDration and bicarbonate to prevent acute renal injury after endovascular aneurysm repair with suprarenal fixation: pilot/feasibility randomised controlled study (HYDRA Pilot trial). Eur J Vasc Endovasc Surg 2018; 55: 648-656.

Authors: Saratzis A, Chiocchia V, Jiffry A, Hassanali N, Singh S, Imray CH et al.

Scientific Surgery

Safety of stenting and endarterectomy for asymptomatic carotid artery stenosis: a meta-analysis of randomised controlled trials. Eur J Vasc Endovasc Surg 2018; 55: 614-624.

Authors: Cui L, Han Y, Zhang S, Liu X, Zhang J

Scientific Surgery

Clopidogrel and aspirin in acute ischemic stroke and high-risk TIA. N Engl J Med 2018; 379: 215-225.

Authors: Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ et al.

Scientific Surgery

Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials. Lancet 2018; 392: 387–399.

Authors: Rothwell PM, Cook NR, Gaziano JM, Price JF, Belch JFF, Roncaglioni MC et al.

Scientific Surgery

Infrapopliteal angioplasty of one or more than one artery for critical limb ischaemia: a randomised clinical trial. Eur J Vasc Endovasc Surg 2018; 55: 518-527.

Authors: Biagioni RB, Biagioni LC, Nasser F, Burihan MC, Ingrund JC, Neser A et al.

Scientific Surgery

A randomized trial of early endovenous ablation in venous ulceration. N Engl J Med 2018; 378: 2105-2114.

Authors: Gohel MS, Heatley F, Liu X, Bradbury A, Bulbulia R, Cullum N et al.

Scientific Surgery

Systematic review and meta-analysis of high-pressure intermittent limb compression for the treatment of intermittent claudication. J Vasc Surg 2018; 67: 620–628.e2.

Authors: Oresanya L, Mazzei M, Bashir R, Farooqui A, Athappan G, Roth S et al.

Scientific Surgery

A feasibility double-blind randomized placebo-controlled trial of extracorporeal shockwave therapy as a novel treatment for intermittent claudication. J Vasc Surg 2018; 67: 514–521.e2.

Authors: Harwood AE, Green J, Cayton T, Raza A, Wallace T, Carradice D et al.

Scientific Surgery

Effect of a home-based exercise intervention of wearable technology and telephone coaching on walking performance in peripheral artery disease. The HONOR randomized clinical trial. JAMA 2018; 319: 1665-1676.

Authors: McDermott MM, Spring B, Berger S, Treat-Jacobson D, Conte MS, Creager MA et al.

Scientific Surgery

Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med 2018; 378: 615-624.

Authors: Raskob GE, van Es N, Verhamme P, Carrier M, Di Nisio M, Garcia D et al.

Scientific Surgery

VeClose trial 12-month outcomes of cyanoacrylate closure versus radiofrequency ablation for incompetent great saphenous veins. J Vasc Surg Venous Lymphatic 2017; 5: 321-330.

Authors: Morrison N, Gibson K, Vasquez M, Weiss R, Cher D, Madsen M et al.

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